into avian influenza virus pathogenicity : the hemagglutinin 1 precursor HA 0 of H 16 subtype has an α - helix structure in its cleavage 2 site with an inefficient HA 1 / HA 2 cleavage
نویسندگان
چکیده
4 Xishan Lu, Yi Shi, Feng Gao, Haixia Xiao, Ming Wang, Jianxun Qi and George 5 F Gao 6 7 College of Veterinary Medicine, China Agricultural University, Beijing 100193, China 8 CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of 9 Microbiology, Chinese Academy of Sciences, Beijing 100101, China 10 National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy 11 of Sciences, Beijing 100101, China 12 Laboratory of Protein Engineering and Vaccines, Tianjin Institute of Industrial 13 Biotechnology, Chinese Academy of Sciences, Tianjin 300308, China 14 Research Network of Immunity and Health (RNIH), Beijing Institutes of Life Science, 15 Chinese Academy of Sciences, Beijing 100101, China 16 17 *These authors contribute equally. 18 Correspondence: [email protected] (G.F.G.), 86-10-64807688 (Tel.), 86-10-64807882 19 (Fax) 20 Running Title: influenza virus H16 structure and virus pathogenicity 21
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